Logo for for Advanced Orthopedics - Nonsurgical & Regenerative Treatments

Phone: 757-460-0434

Virginia Beach

1658 Pleasure House Rd, Suite 104
Virginia Beach, VA 23455


11803 Jefferson Avenue, Suite 260
Newport News, VA 23606

ReNu® FAQs

How does Amniotic Stem Cell Therapy (ASCT) work?

Stem cell treatment takes advantage of the body's ability to repair itself. A stem cell is a special cell the body uses to create new tissues and structures or to heal damaged tissue at a site of injury. Stem cells have the ability to differentiate into any kind of cell that the body might need: skin, bone, blood, cartilage, etc. They also remain stable for many years and have the ability to divide and regenerate.

Image of woman with painful knee

With amniotic stem cell therapy, Dr. Graham injects stem cells from amniotic tissue into your affected area. This is the tissue that protects the baby in utero during pregnancy. The cells have been sterilely processed and converted into a flowable injectable form, which for osteoarthritis is placed sterilely into the joint. For tendonitis it is injected directly into the tendon. In addition to stem cells, amniotic tissue injections also have potent anti-inflammatory properties and are a rich source of collagen, elastin, fibronectin and growth factors that can support tissue repair and regeneration.

While cortisone and other drugs provide only temporary pain relief, stem cells provide long term pain relief and in addition have the ability to restore and heal degenerated tissue. Because of their regenerative capacity and prolonged stability, the pain relief is commonly much longer than previously obtained with past treatments, such as steroids and viscosupplementation. Additionally, stem cell injections contain hyaluronic acid which lubricates joints and tendons, easing the pain and helping restore mobility.

Are stem cell injections safe?

Yes. Amniotic tissue has been used as a medical therapy for over 100 years and has had no reported side effects since its first documented use in 1910. Amniotic stem cell treatment has been used by ophthalmologists to aid with corneal surgery for over 20 years. It also has applications in plastic surgery involving burn patient healing.

Amniotic stem cell therapy is a preferred type of stem cell therapy because the cells come from an immunoprivileged site. The use of amniotic stem cells is well researched, safe, and effective. All amniotic stem cell donors go through a rigorous screening process as determined by the Food and Drug Administration (FDA) and the American Association of Tissue Banks (AATB).

What benefits does amniotic stem cell therapy offer?

Amniotic stem cell therapy (ASCT) is very safe and effective, and delivers a unique and powerful set of advanced capabilities:

  1. ASCT contains no steroids. Instead, the injections rely on naturally-occurring anti-inflammatory agents that are abundantly present in the amnion such as cytokines.
  2. ASCT contains hyaluronic acid which lubricates and helps stabilize cartilage, and promotes cartilage growth and stability.
  3. ASCT contains growth factors which stimulate tissue growth and promote healing.
  4. With ASCT, there is no threat of patient rejection.
  5. Amniotic stem cells, because of their youth, are potentially more robust and active than adult stem cells.
  6. ASCT is a highly concentrated source of young stem cells (from the amnion), which makes this type of stem cell injection preferable to the patient's own stem cells (from adult fat or bone marrow).

Am I a candidate for stem cell therapy?

Patients suffering from any kind of joint, tendon, or ligament pain are possible candidates for amniotic stem cell therapy. Upon evaluation, Dr. Graham will provide you with recommendations for other types of treatment options as well.

Does insurance cover stem cell therapy?

Most insurances do not yet cover regenerative medicine treatments. They do cover office visits, lab and x-ray studies, and physician consultation fees. Patients are responsible for the cost of the medication itself. Payment is fee-for-service and is due at the time of treatment. We do provide payment plans for those patients who cannot pay out of pocket.

What happens after the procedure?

The regenerative medicine injections are done under ultrasound guidance following a local injection of numbing medicine. Afterwards, we recommend only mild essential non-impact activity for the first 24 hours, then non-impact comfortable activity for 1 week, then gradual resumption of all activity as tolerated. Physical therapy and bracing may also be recommended.

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